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Image Search Results
Journal: Micromachines
Article Title: Recent Progress in Microfluidic Models of the Blood-Brain Barrier
doi: 10.3390/mi10060375
Figure Lengend Snippet: Cellular constituents of the blood-brain barrier (BBB). The BBB is formed by brain microvascular endothelial cells (BMECs), which are connected by tight junctions. The endothelium, together with the basal lamina, pericytes, and astrocytic end-feet forms the neurovascular unit. Some substances diffuse freely into and out of the brain parenchyma, others such as nutrients need specific transporters, while molecules such as insulin, leptin and transferrin are transported by receptor- mediated transcytosis. (Reprinted from Reference in accordance with the Creative Commons Attribution).
Article Snippet: Ref. [ ] , High-throught, the model harbors 96 or 40 chips in a 384-well plate. In each chip, a perfused vessel of BMECs was grown against an extracellular matrix gel, astrocytes and pericytes were added on the other side of the gel to complete the BBB model. , Human TY10 cell line (isolated from normal brain tissue from a patient with meningioma) ,
Techniques:
Journal: Micromachines
Article Title: Recent Progress in Microfluidic Models of the Blood-Brain Barrier
doi: 10.3390/mi10060375
Figure Lengend Snippet: The main characters of some microfluidic blood-brain barrier (BBB) models.
Article Snippet: Ref. [ ] , High-throught, the model harbors 96 or 40 chips in a 384-well plate. In each chip, a perfused vessel of BMECs was grown against an extracellular matrix gel, astrocytes and pericytes were added on the other side of the gel to complete the BBB model. , Human TY10 cell line (isolated from normal brain tissue from a patient with meningioma) ,
Techniques: Permeability, Immunofluorescence, Staining, Derivative Assay, Diffusion-based Assay, Marker, In Vivo, Western Blot, Microscopy, Isolation, Impedance Spectroscopy